Canadian Society of

Pharmacology and Therapeutics

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2019 Speaker Biographies and Abstracts

Thursday, June 13, 2019

Emerging recreational drugs of abuse: Pearls and pitfalls
Discussion of clinical management of recreational drug toxicities

Scott Lucyk

University of Calgary

Acetaminophen poisoning: Old dog, new tricks
Discussion of clinical management of acetaminophen overdose

Mark Yarema, MD FRCPC

University of Calgary


Objectives: At the conclusion of this lecture, the participant should be able to:

1. Discuss the pathophysiology and stages of acetaminophen poisoning.

2. Discuss the ordering and interpretation of acetaminophen concentrations after poisoning.

3. List the mechanisms by which N-acetylcysteine (NAC) acts as an antidote for acetaminophen poisoning.

4. Describe the role of additional treatments for acetaminophen poisoning such as alternative NAC regimens, hemodialysis and fomepizole.


Dr. Mark Yarema is the Section Chief for Clinical Pharmacology and Toxicology and the Medical Director of the Poison and Drug Information Service (PADIS) for Alberta Health Services. He is a Clinical Associate Professor in the Department of Emergency Medicine and a member of the O’Brien Institute of Public Health at the University of Calgary. Dr. Yarema practices both Medical Toxicology and Emergency Medicine within the Alberta Health Services Calgary Zone. His research interests include acetaminophen poisoning, drugs of abuse, and toxic alcohols.