The Brain, Precision Medicine, Medical Marijuana: Pharmacology in the 21st Century

Agenda


Tuesday, June 13th

08:00 to 15:00    Clinical Pharmacology and Toxicology Continuing Education Course                    

A course offered to trainees in Clinical Pharmacology and Toxicology designed to provide the most current information in the disciplines. This course will provide a broad overview of the discipline and aid clinical trainees in optimizing patient care. Topics will include clinical trial design, pharmacokinetics, pharmacogenomics, pharmacology of addiction, and reproductive and forensic toxicology. 

14:00 to 19:00     Royal College Subspecialty Committee Meeting

 



Wednesday, June 14th

07:00 to 15:30     Registration Desk Open

07:30 to 08:30     Breakfast

08:30 to 17:30     Posters and Exhibit Open

08:30 to 08:40     Conference Welcome Address

08:40 to 10:25     Pre-clinical and Clinical Investigation of Cannabinoids and Cannabinoid Receptors
With the possible legalization of marijuana on the horizon, cannabinoids and cannabis have gained the attention of the general population in recent years. The research community has been very active as well, with the recent elucidation of the cannabinoid receptor structure and several studies investigating cannabinoids as therapeutic agents. Cannabinoids have been suggested as potential therapeutics in PTSD and chronic pain, and could potentially have an impact on mental health. Will the legalization of marijuana lead to increased use among youth? If so, how will this impact their cognitive development? What will be the effects of chronic use of cannabinoids on the aging population? This session will address some of these questions and other recent advances in the field. 

Moderator: Dr. Denis Dupré, Dalhousie University

Presentations:

Cannabis and Mental Illness: Caveat H-Emptorr

Dr. Tony George, Centre for Addiction and Mental Health, Toronto, Canada

New Horizons for Cannabinoid Medicines

Dr. Melanie Kelly, Dalhousie University

• Speaker 3, TBA 

10:25 to 10:40     Break, Poster Viewing, Exhibits
10:40 to 12:10     Precision Medicine: From Population to Patient Focused Drug Therapy
This session will focus on the continued development of precision medicine and the tools necessary to move from population-level treatment decisions to those that are in the individual patient’s best interest. Topics covered will include the integration of precision medicine into health care in adult and pediatric medicine as well as the importance of pharmacokinetic and functional validation of genomic markers of drug outcomes. 

Moderator: Dr. Folefac Aminkeng, Centre for Molecular Medicine and Therapeutics, University of British Columbia

Presentations:

Cardiotoxicity in Long-term Childhood Cancer Survivors: From Patient Populations to Cardiomyocytes

Dr. Michelle Hildebrantdt, MD Anderson Cancer Center, Houston Texas

• Pediatric Cancer: Using Precision Medicine to Help our Therapeutics Orphans

Dr. Jamie Renbarger, Indiana University, Indianapolis, Indiana 

• Pharmacokinetics and Pharmacodynamic Approaches in Precision Medicine

Dr. Rommel Tirona, Western University, London, Canada

12:10 to 13:00     Lunch, Poster Viewing, Exhibits


13:00 to 15:00    Trainee 10-Minute Oral Platform Presentations
The top-10 rated trainee abstracts will be selected to deliver 10- minute oral presentations. 

15:00 to 15:15     Break, Poster Viewing, Exhibits

15:15 to 16:15      Networking and Roundtable Discussion
This session will be designed for trainees to have an opportunity to interact with conference speakers, discuss research and learn more about specific career opportunities. 
18:00 to 20:00    Welcome Reception, Student Mixer and Trainee Rapid-Fire Presentations
Maritime Museum of the Atlantic

Mix and mingle in this beautiful, downtown waterfront museum while also taking in the rich history and interesting artifacts. Then stay on as approximately 12–15 trainees present one-slide three-minute thesis style presentations to provide an overview of their research in advance of the formal poster session.

Moderator: Dr. Kerry Goralski, College of Pharmacy, Dalhousie University


20:00                   Trainee Social

 

 

Thursday, June 15th

07:00 to 15:30     Registration Desk Open

07:30 to 08:20     Breakfast

08:20 to 08:30     Opening Remarks

08:30 to 17:30     Posters and Exhibit Open

08:30 to 10:20     Therapeutics Targets in CNS Disease
This symposium is aimed at providing the audience with a broad overview from three internationally recognized pharmacologists who are making inroads in understanding CNS disease as well as offering valuable insight into therapeutic approaches. Keynote speaker, Dr. Beverley Orser from the University of Toronto, will discuss the clinical use of general anesthetics and the challenge of post-operative memory loss. Dr. Jean-François Trempe from McGill University will discuss recent structural biology evidence that is helping to shape our understanding of and treatment options for Parkinson’s disease. Finally, Dr. Ian Weaver from Dalhousie University will discuss how his work on epigenetics is providing new insight into how our behaviours are dictated. 

Moderator: Dr. Derek Bowie, McGill University, Montreal, Canada

Presentations:

 Peter Dresel Award Lecture: Anesthesia and Post-operative Memory Loss

Dr. Beverly Orser, University of Toronto, Toronto, Canada

• Parking and PINK1 as targets for the treatment of Parkinson's disease: a structural perspective.

Dr. Jean-Francois Trempe, McGill University, Montreal, Canada

Gene Expression and Brain Development

Dr. Ian Weaver, Dalhousie University, Halifax, Canada 

10:20 to 10:40     Break, Poster Viewing, Exhibits
10:40 to 12:10     Nanomedicine for Drug Delivery and Therapeutics
This symposium will review current research in drug encapsulation to enhance drug delivery in the treatment of a variety of diseases. Topics to be addressed include liposomal encapsulation of chemotherapeutic agents and strategies to improve transdermal drug delivery.

Moderator: Dr. Abdel Omri, Laurentian Univerisity, TBC

Presentations:

• MetaplexTM Technology: Use of Liposomes as Nanoscale Reaction Vessels to Prepare Metal-drug Complexes Suitable for Parenteral Use

Dr. Marcel Bally, BC Cancer Agency, Vancouver, Canada

Non-viral Gene Therapy for the Retina and Optic Nerve with Neurotrophic Factors: Implications for Glaucoma

Dr. Marianna Foldvari, University of Waterloo, Waterloo, Canada

• Thermosensitive Liposomes: A Therapeutic Strategy to Enhance the Effectiveness of Nanomedicines in Oncology

Dr. Christine Allen, University of Toronto, Toronto, Canada

12:10 to 13:00     Lunch, Poster Viewing, Exhibits

13:00 to 14:30     Poster Presentations/Poster Competition
Trainees will be given the opportunity to present their research posters. A limited number of presentation awards are available. 

14:30 to 16:00     Practical Pharmacology
The Practical Pharmacology session will highlight the clinical application of pharmacology and toxicology principles in the provision of health care to patients. Clinical trainees will present cases which highlight issues related to providing optimal therapeutics and toxicological care. Areas which may be highlighted include any of the following: pre or post drug administration pharmacogenomic analysis (eg. TPMT prior to azathioprine), characterization of unusual pharmacokinetics in a diseased patient (ex: atenolol PK in a patient undergoing dialysis), determination of clinical toxidromes, antidotes for poisoning and management strategies for questionable ADE’s (eg. N of 1 trial).
Moderator: Dr. George Dresser, Western University, London, Canada

16:00 to 16:15     Break, Poster Viewing, Exhibits

16:15 to 17:15      CSPT Award Lectures 1
CSPT offers several competitive research awards including the Clinical Fellowship Award, Postdoctoral Fellowship Award, Young Investigator and Senior Scientist Awards. These award recipients are invited to deliver a presentation of their recent research at the annual scientific conference.

18:00 to 21:00     CSPT Annual Dinner: The Lower Deck Tap Room

 

Friday, June 16th

07:00 to 12:30     Registration Desk Open

07:30 to 08:30     Breakfast

8:30 to 12:00      Posters and Exhibits Open

08:30 to 09:30    CSPT Annual General Meeting and Awards Presentation

9:30 to 10:55      Practical Approaches to Optimizing Drug Use in Pregnancy and Breastfeeding

This session will focus on drug safety during pregnancy, breastfeeding and pediatric pharmacology. Topics covered include the mechanisms of drug transport across the placenta, and mechanisms and clinical relevance of drug movement into breastmilk. 

Moderator: Dr. Bruce Carleton and Dr. Brad Urquhart

Presentations:

 Drug Safety in Pregnancy

Dr. Dongmei Sun, Western University, London, Canada

• The Role of Placental Drug Transporters on Fetal Drug Exposure

Dr. Micheline Piquette-Miller, University of Toronto, Toronto, Canada

• Drug Elimination in Breastmilk: Mechanisms and Clinical Relevance

Dr. Shinya Ito, University of Toronto, Toronto, Canada

10:55 to 11:10     Break, Poster Viewing, Exhibits

11:10 to 12:00     CSPT Award Lectures 2

12:00 to 12:15     Closing Remarks