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Glossary of Pharmacology 

Graded Dose-response curve

Definition: 

The dose-response relationship in which the magnitude of biological response is proportional to the dose of drug i.e., as the concentration of a drug increases, its biologic effect gradually increases until all the receptors are occupied (maximal response), provided that there are no spare receptors. A graded dose–response curve is one that has the general shape of a rectangular hyperbola where two important drug properties can be determined: Potency and Efficacy. 

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