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Canadian Society of

Pharmacology and Therapeutics

Glossary of Pharmacology 

Table of Pharmacological Terms

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Term

A

Absorption

Adherence

Adverse drug event

Adverse drug reaction

Affinity

Agonist

Allele

Allosteric modulator

Allosteric site

Antagonist

Apparent volume of distribution (Vd)

AUC

B

Bioavailability (F)

Biological marker (Biomarker)

Biotransformation

C

Cheng-Prusoff equation

Clinical trials

Competitve antagonist

Competitive inhibitor

Concentration-time curve

Conformational change

Constitutive activity

D

Desensitization

Dose-response relationships

Drug clearance

Drug concentration

Drug transport

E

Efficacy

Enteral drug administration

Enzyme

Equilibrium dissociation constant (Kd)

F

First-pass effect

Full agonist

G

Graded dose-response curve

H

Half-life

Haplotype

I

IC50

Informed consent document

Inhibitory constant (Ki)

Inverse agonist

Irreversible antagonist

J

K

L

Ligand

M

Maximum Activation Potential Vmax

Metabolic drug tolerance

Metabolism

Metabolite

Michaelis constant (Km)

N

Non-competitive antagonist

O

Observational studies

Orthosteric site

P

Parent compound

Parenteral drug administration

Partial agonist

Pharmacodynamics

Pharmacogenetics

Pharmacogenomics

Pharmacokinetics (PK)

Pharmacology

Phase I Clinical Trial

Phase II Clinical Trial

Phase III Clinical Trial

Phase IV Clinical Trial

Potency

Prodrug

Q

Quantal dose-response curve

R

Randomized controlled trials

Receptor

Receptor pharmacology

Reversible antagonist

S

Side effect

Spare receptors

Substrate

T

Tachyphylaxis

Therapeutic index

Therapeutics

Tolerance

Toxicology

Transporter

U

V

W

Wild type

X

Y

Z


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